In this interview, Thomas Lewis, Ph.D., and Dr. Michael Carter explain how biomarker panels can help you take control of your health by identifying underlying chronic infections that might be sabotaging your health. Lewis is a microbiologist with a Ph.D. from MIT and certifications from the Harvard School of Public Health and Carter is an integrative physician. They run a company that performs diagnostic testing to guide patients through a process of diagnosing various ailments. Biomarkers such as D-dimer, fibrinogen, clotting factors and auto antibodies, which are largely ignored by the mainstream, can clue you in on where you lie on a health/disease continuum. Importantly, poor COVID outcomes are rare unless you have two or more comorbidities, and in the last year, they’ve developed a more refined way of assessing an individual’s COVID-19 risk using a panel of specific markers associated with inflammation and blood clotting. Their testing helps YOU understand where you are on the health-disease continuum. In their model, you are not either sick or well — you are somewhere on this continuum. Find out where you are and then work to improve your status. “Really, it's your chronic health status that helps you figure out where you are in the continuum for COVID risk,” Lewis explains. The same goes for the COVID shot. According to Lewis, whether you got COVID-19 or the vaccine, the risk factors that determine whether you’ll have a serious bout of COVID-19 or experience more serious adverse events from the shot are identical. The Role of Underlying InfectionsUnderlying or latent infections can play a significant role not only in chronic disease but also in SARS-CoV-2 infection. Judy Mikovits, Ph.D., has pointed out the role of retroviruses and coinfections with pathogens such as borellia and babesia in leading to less favorable outcomes in COVID. Her hypothesis is that SARS-CoV-2 in and of itself is not the primary cause of COVID-19. She’s convinced there must be a coinfection along with SARS-CoV-2 that suppresses or compromises your immune system in order for symptomatic COVID-19 to occur. Carter and Lewis have discovered a number of infectious pathogens that are even more prolific than those highlighted by Mikovits, and which appear central in triggering many chronic conditions that then predispose you to more severe COVID-19. Primary among those are bacteria involved in periodontal disease (periodontitis). You don’t have to have oral issues or root canals to have a high burden of periodontal pathogens. The Lewis/Carter team test for these pathogens using an oral DNA home test kit. Another is chlamydia pneumoniae, a respiratory pathogen that 60% to 70% of older adults have antibodies against. Chlamydia pneumoniae plays a role in several common age-related conditions, including Alzheimer’s disease, heart disease and rheumatoid arthritis. Unfortunately, few are ever tested for the presence of this organism. According to Lewis and Carter, inflammatory markers and clotting markers such as C-reactive protein, fibrinogen, uric acid, the neutrophil-to-lymphocyte ratio, D-dimer, and sedimentation (SED) rate are strongly associated with innate immune response activity and chronic infections, which in turn correlate with COVID-19 severity.
So, to clarify the hypothesis presented by Lewis and Carter, the conventional view is that these infections, once they've generated an IgG antibody response, no longer pose a threat to your body. But this isn’t the case. They can indeed lay dormant only to later contribute to chronic diseases that, on the surface, appear to have nothing to do with a pathogenic infection. The book by Paul Ewald titled, “Plague Time: The New Germ Theory of Disease,” written in 2000, explains well this conundrum. How to Identify Underlying InfectionsThe clinical approach to identifying whether an underlying infection is at play in a particular disease is to look at antibody levels. Immunoglobulin G (IgG) is reflective of long-term protection and also happens to be the most common antibody, found in blood and other body fluids. It protects against both viral and bacterial infections and tends to be elevated when the infection has reached a chronic state. Immunoglobulin M (IgM) is associated with acute responses to infections and is found primarily in your blood and lymph. It’s the first antibody to be made when your body encounters a new pathogen. Carter explains:
In summary, if you have elevations (or suppressions) in white blood cell markers, then you likely have an infectious process going on in your body. There’s also typically a direct correlation between your antibody level and the risk of disease, so the higher your antibody level, the greater your risk of chronic disease and poor COVID / JAB outcomes. PCR testing can be useful for identifying a specific pathogen. However, if excessively high cycle thresholds (CTs) are used (as has been the rule when testing for SARS-CoV-2), the test becomes useless, as it can find even a single molecule if run at a high-enough CT. So, the CT needs to be below 26 to avoid false positives. Review of Lewis and Carter’s ResearchBefore we go further, here’s how Lewis describes their research, and how it can improve your health and medical decisions:
Treating Chronic Versus Acute InfectionsCarter and Lewis have developed a pretreatment program, followed by a variety of treatment strategies aimed at chronic infections. As you might expect, the chronic infection treatments involve more aggressive approaches, and will depend on whether the infection is caused by bacteria, viruses or parasites. The biggest factor for effective treatment is eradicating pathogens hiding in biofilm, which takes time. (We do not address the use of specific remedies in this interview, as each patient must be tested, seeing how there’s such a broad array of potential causal factors.) As noted by Lewis, even if you use a broad-spectrum anti-infective, such as ozone, you’ll rarely eradicate enough of the chronic phase of these organisms, as they shelter inside biofilms or inside your cells — including your white blood cells. that are very difficult to get into. These pathogens are often referred to as “obligate intracellular pathogens.” The “obligate” part infers that these harmful organisms rob your energy by mimicing to be your mitochondria. He explains:
The Role of Vitamin DA basic intervention that is really important for shoring up your immune system is vitamin D. Vitamin D is really a pro-hormone and hormones regulate physiological processes. I believe vitamin D optimization — making sure your blood level is between 60 ng/mL and 80 ng/mL (150 nmol/L and 200 nmol/L) — is one of the easiest, least expensive and most important things you can do to avoid infections of all kinds, including COVID-19. The activated form of “vitamin” D is produced in your liver when you have an infection and it is strongly antibiotic. Lewis and Carter recently completed a study in which they looked at the vitamin D level compared to neutrophil and lymphocyte ratio. Lewis explains:
They’ve also found a similar correlation between chronic infection and free cholesterol (not total cholesterol). This correlation appears particularly strong in those with cancer, who typically have a free cholesterol level of 50 ng/mL and above. An optimal level is thought to be somewhere between 5 ng/mL and 20 ng/mL, with the healthiest of people typically falling between 5 ng/mL and 15 ng/mL. When free cholesterol is elevated, you’re more prone to tissue destruction, as cholesterol is an important repair molecule. Since your cholesterol level can indicate your tissue repair capability, it is also included in Lewis’ and Carter’s COVID panel.
How Do You Know if an Infection Is Chronic?One way to determine whether you’re suffering from an acute or chronic infection is to look at the half-life of the factors being measured. Lewis explains:
What’s in the Panel?Speaking to the issue of what the panel Lewis and Carter developed contains, Carter explains:
In addition to helping you evaluate your chronic disease risk, this panel will also help you assess your COVID-19 risk. They also offer an advanced panel that is even more comprehensive. It costs about $400 and includes a one-hour consultation to help you understand what all the markers mean. As noted by Lewis, “It's all about where do you lie on the health/disease continuum. We very accurately are placing people on that, and there's not a marker we test for that's not modifiable through lifestyle or other appropriate interventions. We're not treating symptoms. We're going right at the disease.” Where to Get the PanelIf you’re interested in ordering this panel, go to HealthRevivalPartners.com. If you want to get the comprehensive COVID / JAB risk screening panel, go to www.healthrevivalpartners.com/post-jab-tests. You will be asked to fill out a questionnaire, after which you receive a requisition to have your blood drawn at a LabCorp. The report you get will be a comprehensive and detailed report from Health Revival Partners in addition to the standard lab report. Carter explains:
Building a Stronger Foundation for Functional MedicineAgain, to learn more, and to join the Health Revival Partners’ chronic disease support program, go to HealthRevivalPartners.com. In closing, Lewis notes:
from http://articles.mercola.com/sites/articles/archive/2021/08/29/identifying-underlying-chronic-infections.aspx
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